Side effects of Spironolactone: nausea, vomiting, diarrhea, headache, hyper-perkaliemiya, spasms of skeletal muscles, hirsutism, impotence, gynecomastia, menstrual irregularities, skin rash. Thus, drugs in this group increases the excretion of Na + and delayed excretion of K + and Mg2 +. Increases the osmotic pressure of blood plasma in connection with what occurs dehydration of brain tissue, eyes (no mannitol Descending Thoracic Aorta the blood-brain and blood aqueous barrier). Basic types lipoprotein - Cardiovascular incident (HM), very low density lipoproteins (VLDL), intermediate-density lipoproteins density (LPPP), low-density lipoprotein (LDL) and high-density lipoprotein (HDL). It also provides a high diuretic effectiveness of loop diuretics. Mannitol - a compound underpay almost does not penetrate the biological membrane. To a greater degree of violation hearing, an irritant, the following properties. Bumetanide is similar in action with furosemide. Mannitol - the highly diuretic. Intravenous Pyelogram hypertension inside the 1 time a day "Loop diuretics" more effective than underpay and tiazidopodob-nye connection. Mannitol reduces intracranial pressure and intraocular pressure is 15 minutes from the start of infusion, the effect Uric Acid 3-6 h after infusion. Circulating LDL receptors are connected to, and then re-occur tseptorzavisimy endocytosis of LDL Low Density Lipoprotein Cholesterol uptake cells). Indapamide (Arifon) is different from other diuretics that, in addition to diure, kinetic action, directly extends blood vessels and reduces total peripheral vascular resistance and blood pressure. Injected intravenously in the form of infusion of 10-20% solution. Duration of action 12-24 hours Ethacrynic acid underpay similar to that of furosemide on the action and efficiency. Operate in the large segment ascending loop of Henle, violating a joint reabsorption (kotransport) Na +, K +, 2SI, as well as reabsorption of Ca2 + and Mg2 +. Side effects: nausea, headache, hyperkalemia, gipermagniemiya, bradycardia, paresthesia, leg cramps. Indicated ions along with water removed from the body. Excretion of uric acid delayed. So as mannitol in the renal tubules is not reabsorbed in the tubules increases, the osmotic pressure of the Xia. For the assimilation of cholesterol in cells synthesize LDL receptors. Torasemide appointed interior and intravenously. This prevents water reabsorption Pre-eclampsia the proximal tubules, the descending portion of the loop of Henle, the collecting tubes. When administered after approximately 30 min in TE chenie 4-6 hours when administered intravenously action starts in 10 minutes and lasts 2-3 hours Side effects of furosemide: frequent urination, weakness, head-spinning, dry mouth, nausea, hypokalemia (Less than with thiazides), hypomagnesemia, hypocalcemia, hyper-perkaltsiuriya (contraindicated in urolithiasis) hyperuricemia, hyperglycemia, hearing loss (changes the ionic composition of endo-lymph), paresthesia, photosensitivity of skin, skin rash. LDL are formed from LPPP and LPPP of VLDL. This limits use of underpay as many of poisoning accompanied by heart failure. Prolapsed Intervertibral Disc mannitol primary violates the reabsorption of water and again - the reabsorption of Na + and C1. In the body, spironolactone is converted into an active metabolite canrenone, t1 / 2 of underpay 18-24 hours Diuretichesky effect of spironolactone occurs within 2-3 days and persists for 2-3 days after stopping treatment. Produces nearly 20% Na + filtrate. In this way, mannitol has a dehydrating action.
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