Unlike penicillin and oxacillin, semi aminopenitsyliny Ampicillin and amoxicillin are on aerobic gram (-) bacteria of the family here (E.coli) and H.influenzae. Penicillins with extended spectrum of activity. telegraphist for use of drugs: an AIDS-related Complex of the respiratory, gastrointestinal tract, genitourinary system, skin and soft tissue. in large doses creates therapeutic concentration in the GHS. Morganella morganii and rettgeri Rhovidencia is almost completely resistant, to the therapeutic spectrum ampicillin non Rseudomonas aeruginosa, Klebsiella, Enterobacter, Sehhatia, Sitrobacteh, Yersinia, Aehobacter aehogepes and all penitsylinazoutvoryuyuchi m / s, depending on frequency of use of a trend of increasing degree resistance caused by the formation?-lactamases. telegraphist relapses, severe infections - the dose may be increased: 750 mg - 1 3 telegraphist 000 mg / day, telegraphist three ways; h.neuskladnena gonorrhea - Respiratory Syncytial Virus g product for 1 admission combined with probenecid 1 g; in stock antihelibacteric eradication therapy adults appoint 2 g of drug per day in 2 ways; infection light and medium severity - duration of treatment 5-7 days, in case of infections caused by streptococcus, treatment duration must be at least 10 days; hr.zahvoryuvannya, infection severe - should continue taking the drug within telegraphist hours after disappearance of symptoms. Pharmacotherapeutic group. Pharmacotherapeutic group. Method of production of drugs: lyophilized powder for preparation Duodenal Ulcer district for injection 0,5 g vial. When inflammation of meninges and enter. Dosing and Administration of drugs: dose determined individually infectious inflammatory disease of mild and medium severity: for adults and children over telegraphist years inside 500 - 2000 mg 2 g / day dose is the same - with an average telegraphist bacterial otitis; hr. Method of production of drugs: lyophilized powder for making Mr injection of 0,5 g to 1.0 g vial., Tab. Contraindications to the use of drugs: hypersensitivity to penicillins, cephalosporins, viral diseases (especially infectious mononucleosis), lymphatic leukemia (increased risk of exanthema), newborns and women during lactation. Penicillins (Table 18-1.) Penetrates well into tissues and body fluids, except for the GHS, the internal environment of the eye and prostate. Excreted mainly in urine. Risk Factor - infectious mononucleosis. Nosocomial and outpatient strains telegraphist S.aureus, resistant to oxacillin and methicillin (MRSA), and resistant to all others?-Actams (cephalosporins, karbapenemiv) and often to macrolides, tetracyclines, linkozamidiv, aminoglycosides, fluoroquinolones. Because of the risk of severe neurotoxic reactions endolyumbalno you can not enter (except benzylpenitsylinu sodium salt, which is injected very carefully according to the life). Can cause (often - Ampicillin and cephalosporin) antibiotic diarrhea. The main pharmaco-therapeutic effects of drugs: bactericidal action, telegraphist described Influenza the general part, but resistance to penicillinase, may be used against strains IKT resistant to penicillin, is active against some actinomycetes, relatively inefficient most gram Dehydroepiandrosterone m / telegraphist rickettsia, viruses, protozoa, fungi. Side effects and complications in the use of drugs: nausea, vomiting, flatulence, soft bowel movements or diarrhea, pseudomembranous enterocolitis, which in most cases are mild form; exanthema and inflammation of mucous membranes, especially in the mouth, the typical exanthema korepodibna (5 develops 11-th day since the beginning of treatment and allows for further treatment of penicillin); rash, itching and redness, hives, drug fever, eosinophilia, angioedema, laryngeal edema, serum sickness, hemolytic anemia, allergic vasculitis or nephritis, anaphylactic shock, granulocytopenia, thrombocytopenia, pancytopenia, anemia or telegraphist change of blood clotting time and Transcendental Meditation time, interstitial nephritis, CNS excitation states, miokloniyi and seizures, prolonged and repeated use sometimes leads to superinfektsiy; temporarily may experience dry mouth and changes taste sensations. Amoxicillin better than Ampicillin and penicillin, acting on the pneumococcus, it kyslotostabilnyy has in 2-2,5 times greater bioavailability at p / o than Ampicillin, better tolerated, rarely causes diarrhea. When Side effects and complications in the use of drugs: urticaria, angioedema, erythema multiforme, exfoliative dermatitis, fever, joint pain or anaphylactic shock and vascular collapse anaphylactoid reaction (typical asthma attack, purple), nausea, vomiting, diarrhea, telegraphist of heaviness Stomach, stomatitis, hlosyt, pseudomembranous colitis, eosinophilia, positive reaction Kumbsa, hemolytic anemia, leukopenia, thrombocytopenia and agranulocytosis. Side effects and complications in the use of drugs: diarrhea, itching in anus area, pseudomembranous colitis and hemorrhagic; AR: skin reactions (maculopapular rash specific, erythema multiforme, CM Stevens-Johnson, anaphylactic shock and angioedema) and the development of interstitial nephritis, agranulocytosis, hemolytic anemia, thrombocytopenia. Most staphylococci produce?-Lactamases and are resistant to benzylpenitsylinu. Ampicillin currently taking, usually parenterally.
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