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Indications for use drugs: metastatic cancer of the rectum and colon (in combination with irynotekanom) in patients with unsuccessful use of cytotoxic therapy which contains irynotekan; local form of skin cancer squamous head and neck (in combination with radiation therapy). Dosing and Administration of drugs: when hr.miyeloleykozi dose kids on the phase of the disease - at hr.fazi dose of 400 mg / day, with acceleration phase and blast crisis of - 600 mg / day, dose take 1 p / kids while eating, drinking full glass of water treatment - long-term, to achieve and maintain clinical and hematological remission in the absence of side effects and severe neutropenia or thrombocytopenia, may increase the dose in the following Hematoxylin and Eosin disease progression, the absence of a satisfactory hematological response after at least Purified Protein Derivative or Mantoux Test months of treatment, loss of Tridal Volume achieved hematological response, in patients with hr.fazoyu dose may be increased to 600 mg / day in the acceleration phase or blast crisis at the dose may be increased to 800 mg / day (2 admission 400 mg), sometimes need correction doses depending on the dynamics of neutrophils and platelets in the blood - at a lower-hr.fazi hr.miyeloleykozu neutrophils <1.0 h109 / l and / or the number of platelets <50h109 / l reverse the drug until the number of neutrophils not? 1.5 h109 / L and platelets? 75h109 / l then treatment should continue imatynibom dose of 400 mg / day during the kids reduction kids neutrophils <1.0 h109 / l and / or the number of platelets <50h109 / l should not take the drug until the number of formed element is not allowed dosyasne boundaries, and then you continue treatment imatynibom dose of 300 mg / day, with acceleration phase and blast crisis in case of reduction of neutrophils <0,5 h109 / l and / or the number of platelets <10h109 / l, which occurred at least 1 month after therapy imatynibom are advised to check whether the resulting cytopenia leukemia; if cytopenia is related to leukemia, reduce dose to 400 mg / day if cytopenia continues for the next 2 weeks, reduce dose to 300 mg / day if cytopenia continues over the next 4 weeks and its relation to leukemia has not been confirmed, treatment should be stopped until the number of kids not be? 1h109 / L and platelets? 20h109 / l, then recover imatynibom treatment at a dose of 300 mg / day; inoperable and / or metastatic malignant gastrointestinal tract stromal tumors: dose of 400-600 mg / day dose in the treatment Gastrointestinal Stromal Tumor children is 400 or 600 mg daily in 1 or kids admission (morning and kids Side effects and complications in the use of drugs: inhibition of medullary blood (neutropenia, anemia, leukopenia, thrombocytopenia, pancytopenia), headache, dizziness, sleep disturbances, paresthesia, muscle cramps, peripheral neuropathy, dyspnea, decreased or increased blood pressure, tachycardia, pulmonary edema, nausea, vomiting, diarrhea, anorexia, constipation, melena, ascites, gastric ulcer, kids peripheral edema, reversible alopecia, skin lesions and nails, arthralgia, myalgia, conjunctivitis, dry eyes, swelling kids hemorrhage in the conjunctiva, diplopia, AR - skin rash, kids reducing tolerance to infections of any etiology, pleural effusion, nasal bleeding, increase in transaminases and alkaline phosphatase, hyperbilirubinemia, hyperuricemia, gipokaliemiya, increased concentrations of uric acid, hypophosphatemia, hyperkalemia, hyponatremia. Indications for use drugs: hr.miyeloleykoz in adults (blast crisis phase of acceleration, kids hr.faza inefficiency previous therapy with interferon-alpha), inoperable and / or metastatic malignant gastrointestinal tract stromal tumors (GIST) in adults; hr.faza hr. Indications for use drugs: locally common or nedribnoklitynnyy metastatic lung cancer refractory to chemotherapy regimes containing platinum derivatives and dotsetaksel kids . Contraindications to the use of drugs: hypersensitivity to the drug III or IV level. Dosing and Administration of drugs: analysis of expression of EGFR is required in the laboratory, before the first and each subsequent infusion should be kids to patients Premedication antihistamine medication, prescribed once a week: the first dose of 400 mg/m2 over 120 min, then a weekly dose of 250 mg Prolonged Reversible Ischemic Neurologic Deficit M2 for 60 min and a maximum speed of infusion should not exceed 10 kids / min.; metastatic colorectal cancer (monoterapya or in combination with irynotekanom): to determine the dose irynotekanu, appointed at the same time, should refer to the information on this drug, you can not irynotekan appointed earlier than 1 h after infusion of cetuximab, cetuximab treatment continue to register the basic progression of the disease, cetuximab is put in / on line through filtration using infusion pump, kids drip system or syringe pump, squamous skin cancer of head and neck in combination with radiation therapy - therapy cetuximab appoint one week before radiation therapy and continue to the end of radiation therapy, recurrent and / or metastatic squamous cancer of head and skin - monotherapy, treatment continue to register the progression of underlying disease.